Nerve Connective Tissue
Endoneurium
This is the connective tissue surrounding each individual axon and its myelin sheath.
Perineurium
This is the strong, protective, connective tissue surrounding bundles or fascicles of myelinated and unmyelinated nerve fibers. It helps strengthen the nerve and acts as a diffusion barrier. Individual axons may cross from one bundle to another along the course of the nerve.
Epineurium
This is the loose connective tissue surrounding the entire nerve that holds the fascicles together and protects it from compression.
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